I am not advocating switching to what many veterinarians would call “alternative therapy;”
if you are having success with allopathic treatments in fighting cancer, you may wish to
continue with that course.  The decision about treatment must be yours but I would like
to share with you my experience with Neoplasene in treating cancer. Stay with me while
I give you some background.

Jazzie is a female Leonberger, a breed that is very prone to cancer.  Our Health and
Research Committee estimated that 37% of Leos will be diagnosed with cancer. 
We had made the decision to leave Jazzie intact for a few reasons, one being that
research indicated early spay or neuter was linked to fatal forms of cancer, including
osteosarcoma and hemangiosarcoma, two fatal cancers found with frequency in the
Leonberger.  Secondly, Jazzie was a National Specialty Winner, taking Best of Opposite
at the 2000 Leonberger Club of America National Specialty.  Since she was from a
fairly healthy gene pool in Sweden, we hoped to breed her by importing semen from
Norway.  For whatever reason, FedEx lost the 20 pound tank of frozen semen! That
was the end of a window of opportunity to breed Jazzie since her next heat cycle would
have put her into the “too old for breeding” category.

Knowing our decision to leave her intact put her at increased risk for mammary cancer and
pyometra (a treatable but possibly fatal uterine infection), we watched her closely for
signs of either disease.  It happened after her heat cycle when she was 9 years old. 
She developed “open pyometra,” which is very difficult to miss since the infected uterus
drains lots of fluid. 

Our regular vet sent us to VMSG, a surgery and medical specialty hospital in Oxnard,
California.  Jazzie was spayed in early May, 2007 by a Board Certified Surgeon, Dr. Mary
Dulish.  During the spay, a small anomaly was seen in her intestines.  Dr. Dulish called us
and we agreed to have it removed.  It added another $4,000 to our vet bill which is why
there was a question that required an answer from us.   

Jazzie’s recovery was difficult because we were dealing with both a spay and intestinal
surgery but the care given to her during her 8 days in ICU was extraordinary.  Just before
we took her home, the lab report came back from the multiple biopsies including the
intestinal tissue.  The intestinal biopsy showed adenocarcinoma, an aggressive and fast
growing cancer. 

In a way, it was a miracle that she was intact, that she had pyo and that she was in the
care of a Board Certified Surgeon.  Still, we were faced with decisions about chemotherapy. 
As the Oncologist explained it, though there were clear margins on either side of the cancer,
it had penetrated the intestinal wall and most certainly, it would metastasize.  The
chemotherapy recommended was new and very toxic.  It was not an easy decision to make
but we chose not to proceed with putting Jazzie through these treatments since they
still did not offer any guarantee the cancer would be destroyed.  Intestinal adenocarcinoma
is very difficult to treat. 

While Jazzie slowly recovered, I researched alternative therapies, not really believing an herb
would be a solution. I had been feeding organic/raw food so there were no changes made
there. I read about Neoplasene, though there was little information, perhaps 10 articles
on the Internet.  I had my vet order a jar for Jazzie but after a few attempts, with her
throwing it up minutes after eating, I gave it up.  Meanwhile, my own internist
recommended Oncoplex, a supplement she gives her cancer patients.  Oncoplex has
a proven track record in assisting human cancer patients so Jazzie was started on
Oncoplex, as well as some mushrooms that Memorial Sloan Kettering Cancer Center
recommends to their patients.

For the next 8 months, Jazzie was doing great, eating well, and walking at least a mile or
more every day.  In January, she began to cough.  Thinking she had somehow come down
with kennel cough, we took her to her vet who did a chest x-ray and discovered malignant
tumors in each lung.  They were both approximately 3 centimeters.  The prognosis for
metastasized adenocarcinoma is completely depressing.  The lung cancer grows quickly,
filling the lungs and killing within 3 months.  The radiologist who viewed the x-rays could
not understand why the disease had not progressed faster and wanted to know what I had
been doing!  Oncoplex and Elliott’s magic powders!

I knew there was no longer any hope of saving Jazzie’s life with these measures so I
started researching again and read about Neoplasene—it was my only hope.  This time,
there were 1,400 articles and postings on the Internet from people using it and from
holistic veterinarians working with it.  There it sat in the cupboard!

Jazzie was started on Neoplasene immediately but we had the same problem—she threw it
up.  Dr. Terrence S. Fox of Buck Mountain Botanicals in Montana, the developer of this
form of Neoplasene—spent time with me on the phone and explained the way to resolve
the vomiting problem.  I followed his instructions exactly and it worked—Jazzie did not
vomit!  Within the first week, she stopped coughing. 

She began Neoplasene in January; it is now the end of March and she was just x-rayed to
check her progress.  She gained 7 pounds bringing her weight up to 140 pounds and the
cancers have not grown!  My vet was amazed—there should have been new, small tumors
but Jazzie’s tumors have not grown, she is gaining weight (too much!) and acts like a dog
that feels well.  The Board Certified Radiologist who comes in weekly to confirm x-ray readings
said the same thing--there is no sign of growth of existing tumors and no sign of any new
tumors.  She will be 10 years old on April 26 and thanks to Neoplasene and Dr. Fox, we
will have a real celebration.  

I know if you found this page, it is probably because your dog/cat has cancer and you are
as desperate as I was to find some way to gain hope, to save the life of your pet.  For
that reason, I ask you to follow the links here to educate yourself about Neoplasene. 
Start at Buck Mountain Botanicals and print out the information to take to your vet. 
The program to prevent vomiting is really simple.  Here it is:

Neoplasene is an emetic—a substance that will induce vomiting.  It must be given twice a day
with a meal.  If your dog is not hungry because you’ve been giving it treats throughout the day,
it will not eat a sufficient amount of food to help the body absorb the Neoplasene which must
enter the blood stream through digestion.  Simply stop all between meal treats and cut back
to two meals a day.

Reglan is an anti-emetic that worked extremely well for Jazzie. She received her dose thirty
minutes before feeding.  We had to take her off the Reglan when she began showing signs
of agitation and I learned the Reglan is not always an ideal drug.  We have been trying other
ways to prevent nausea and started Jazzie on Remeron (mirtazapine). Discuss dosage and
choice of anti-emetic with your vet.  Each animal is different--what works for Jazzie may
not work for your pet and in some cases, an anti-emetic may not even be necessary
depending on how well your pet handles the Neoplasene. Some people using neoplasene
are prepping with Pepcid given 20 minutes before feeding.  Many people do not need anything
when they dilute the neoplasene sufficiently.  This becomes a challenge but you must discover
for yourself how best to deal with it.

Dogs with cancer need to be well nourished, therefore, raw food is not the best choice. 
There have been many discussions but few real conclusions about the nutritive values of a
raw food diet.  I do not feed raw any longer--I cook for Jazzie.  You need the Neoplasene to
become part of the food so cook up some rice, vegetables and whatever meat you
wish—ground beef, chicken, turkey—that will be the base for each meal.  I barbeque once
every 2 weeks then freeze meal size packets of wild caught fish, beef, steak, hamburger,
ground lamb.  This makes it real easy to have food on hand.

The dose of Neoplasene varies with each dog; Dr. Fox and your veterinarian will prescribe the
right dose for your animal.  I put Jazzie's Neoplasene into a tablespoon of water and use a little
spoon size whisk to blend.  I add that to her food, stir well.  Because it is bitter, and because
it may cause your dog to turn away, you can use some of my ideas to camouflage the taste. 
Once it’s mixed into her food, I will often add some pure food on top.  I shake some Italian
cheese onto her food or mash a hard-boiled egg as a topper.  I grind organic hot dogs--
chicken and beef, using it as a sprinkle.  Recently, I began cooking bacon for her, saving
the grease and putting a tablespoon of melted grease on her food.  I turn the bacon into
bits and sprinkle that on.  I make organic bacon, both pork and beef from humanely
raised animals so I’m not adding toxins to her food.  The benefits of bacon are
twofold—it’s good for the coat and it makes them thirsty so they drink lots of water. 
The water also aids the transport of the Neoplasene. 

When she seems reluctant to eat, I will pour  in some melted butter. By now, Jazzie is used to
the smell and the taste and is always hungry when her food is put down.  She never used to
have such a good appetite, being picky about her food.  Perhaps she knows that there
is a life-sustaining gift in her bowl—my Leonbergers have always grazed on wild herbs that
provided nutrients they needed.  But that’s another story for another time.

Dr. Fox did not increase her dose after this last set of x-rays because his goal is to kill the
cancer cells just a little faster than they are growing.  In time, the tumors will begin to
shrink—we will track this with x-rays every 6 to 8 weeks. 

The way that I feed her is really simple and it works.  She can have her after dinner chew or
cookie which feeds her soul but her carefully crafted diet is what keeps her alive. One
important thing is
any and all NSAID’s or anti-inflammatory drugs and supplements will
prevent the Neoplasene from working. That includes prednisone, Rimadyl, Derramax,
Previcox, Metacam--any drug that is designed to block an inflammatory response. You
can use other forms of pain management—talk to your vet.  Jazzie receives Tramadol
if she seems to be stiff or in any way uncomfortable.

The only side effect I have noticed from the Neoplasene is Jazzie seems to feel an internal
heat and will spend more time outside on the grass.  I had read someplace that the process
of apoptosis which is how Neoplasene works, heats up the cancer cells to destroy them. 
That would make sense.

I have started a Neoplasene Yahoo Group so we can exchange information and perhaps,
give Dr. Fox a break from the hundreds of phone calls he gets, all asking the same questions! 
You can sign up to join the group at:

Meanwhile, I have put together an in-depth diet sheet.  Click here for that information.

You are not alone in dealing with cancer—we are all working together.  Your dog needs the
support of a team that communicates and listens, so if you do contact Dr. Fox, please listen
to what he is telling you—he is the expert on Neoplasene and he will work in concert with
your veterinarian.  He can put you in touch with a holistic vet in your area if your veterinarian
will not agree to this unique treatment. I'm sure you've discovered that the Internet is not a
safe place for anyone who is desperate to spare the life of their pet. This is not a time to act
on your own; work with the experts--your veterinarian and Dr. Fox.

P.S.  After 3 months on neoplasene, we went through a 2 week period when Jazzie
developed diarrhea and refused food.  She began to lose weight which is the worst
scenario for a cancer patient, but we could not get her back on the neoplasene. 
She had developed a serious aversion to the odor and/or taste.  Finally, we took her
off the neo and began using a combination of other alternative therapies.  Those
therapies included Artemesinin, Artesunate, Artemix, Avemar, melatonin and a
complete homeopathy program set-up by Dr. Charles Loops. 

Jazzie did extremely well on the alternative therapies, living 16 months past the
day the oncologist claimed she would die. We lost the battle on October 4th, 2008
but not necessarily to the cancer.  She died from pneumonia which I believe occurred
because we were too successful in killing cancer cells.  With lung tumors, there is an
infinitely fine line between killing cancer cells safely and progressing so fast that
the lungs become overwhelmed with dead cancer cell debris.  There is no way to
know how well the therapies are working, so with any internal cancer, please take
it very slowly.

Barbara Bouyet


Last updated 08/01/2017 .

© 2004 All Rights Reserved.


Buck Mountain Botanicals
More on Neoplasene
Treating With Neoplasene
Canine Cancer Monthly
Lymphoma and Neoplasene
Whole Dog Journal
What is Apoptosis?
Sloan Kettering Cancer Center
Also try Paw Paw
And Artemisinin